If any team loses their two best pass rushers the sacks and QB pressure is going to drop off dramatically. No matter how much depth they have. That's true of all 32 teams.
The problem is our two best pass rushers will likely miss games. It's pretty much a given they aren't playing full seasons.
Its going to get pretty gnarly if both of them miss four or more games each. Need them both to stay on the field as much as possible. (And not playing at 60%)