Titans/Chiefs - The Titans had a good warmup for Mahomes with Jackson and played a great game last week, although Baltimore really self-destructed. Henry is no joke and the Titans will be able to control the pace of the game and slow things down. But, the rust is off for KC and they won't be making the kind of mistakes they made against Houston. It could be close for 3 quarters but the Chiefs should pull away in the 4th and win this one.
49'ers/Packers - The Packers have been a great surprise this year, surpassing all expectations when it was looking like a long, gruelling re-build for the next 2-3 years with lots of questions to be answered. Kudos to MLF and Gutie for making it happen, they have a great thing going. This will not be the Packers we saw in week 12 and I expect them to come out swinging and be competitive. Garoppolo has shown the ability to get the ball out fast when needed and the 49'ers should be able to continue the trend of molesting the middle of the field if the Pack can't stone their running game early. I just think SF has put together a pretty good group and is a year ahead of the Packers in their development. Hope I'm wrong, but Winner: 49'ers