Fandame, I think KC's offense will matchup much better against SF than the Packers do right now. The difference is that they have playmakers all over the place, Mahomes is a younger Rodgers, Kelce is a great TE, and they have a ton of speed.
Where I think KC might struggle is the DL matching up with SF OL. If KC has one flaw is that I think their defense can really struggle at times.