I suspect we will see plenty of the 4-1-6 formation on defense if we can't keep Cooks contained with a LB. Not a bad idea, since it plays to the 2 biggest strengths of our defense.
Offensively, everything will hinge from OL performance, or lack thereof. It's time for those guys to put their big boy pants on, and hitch 'em tight. It doesn't get any easier this week; as matter of fact, they may be facing an even better pass rush.
With that said, and considering ARod's health, I'd like to see our offense scheme to provide maximum protection and help open up the running game. Most of our depth is at TE and WR, so play to those strengths. Use 2 TE formations, and motion WRs towards the interior of the field.
I recall a few seasons back when a BIG deal was being made of how quickly ARod was getting his throws off. The networks even used a timer on their broadcasts! I don't know why it hasn't had the same emphasis over the last few seasons, but this may be a good week to utilize plays made to do just that.